Tumor lysis syndrome in solid tumors is a rare occurrence, Shoe Care Kits with a poor prognosis.We present the case of a patient of recurrent colon cancer who received chemotherapy with FOLFOX regimen (lencovorin, fluorouracil, and oxaliplatin) with subsequent tumor lysis.We present a recurrent rectal cancer patient suffered from tumor lysis syndrome after salvage FOLFOX regimen.After treat with CVVH with improved conscious T-Shirt status.In this case report, we had review the tumor lysis in solid tumor.